99% Climbazole CAS 38083-17-9 Factory
Climbazole: What is it?
Climbazole is a widely recognized broad-spectrum antifungal agent. With its excellent dandruff-reducing and anti-itch properties, it has become an important ingredient in the daily care industry. Its action is precise and efficient; by inhibiting the biosynthesis of ergosterol in the fungal cell membrane, it disrupts the fungal cell structure, killing or inhibiting the growth of dandruff-causing fungi such as Malassezia at the source. Unlike traditional dandruff agents, Climbazole possesses excellent stability. It is light- and heat-resistant and remains stable over a wide pH range, especially when exposed to metal ions, making it an ideal additive in shampoos, shower gels, and other products. YTBIO's Climbazole boasts high purity (99%) as its core advantage, enhancing the stability and safety of product formulations.
|
ITEM |
STANDARD |
TEST RESULT |
|
Climbazole |
≥99.0% |
99.5% |
|
Physical & Chemical |
|
|
|
Appearance |
White powder |
White powder |
|
M.P |
94-98℃ |
96.0-97.1℃ |
|
Loss on Drying |
≤0.5% |
0.06% |
|
P-Chlorophenol |
≤0.05% |
0.003% |
|
Heavy Metal |
|
|
|
Total Heavy Metals |
≤10ppm |
<10ppm |
|
As |
≤2.0ppm |
<2.0ppm |
|
Pb |
≤2.0ppm |
<2.0ppm |
|
Cd |
≤0.5ppm |
<0.5ppm |
|
Conclusion |
Conform with specification |
|
|
Storage |
Store in cool and dry places. Keep away from strong light and heat |
|
|
Packing |
By 25kgs/Drum, inner by double plastic bag |
|
|
Shelf Life |
24 months under the above condition,and in it's original package |
Efficacy and Functions
1. Dandruff Reduction and Anti-itch
The core function of Climbazole lies in its inhibitory effect on pathogenic scalp fungi such as Malassezia. It can penetrate fungal cells, blocking the synthesis of substances essential for their survival, eliminating scalp inflammation and excessive shedding of the stratum corneum caused by excessive fungal growth, thus addressing dandruff and itching at the root. Data shows that continuous use of shampoos and conditioners containing climbazole significantly reduces dandruff and maintains long-term scalp health.
2. Compatibility
Climbazole exhibits excellent compatibility. It can be used in combination with anti-dandruff agents such as ZPT, producing a significant synergistic effect and enhancing overall dandruff control. Simultaneously, it coexists well with anionic, nonionic, and amphoteric surfactants without precipitation or stratification, ensuring product formula stability.
3. Safety
As a low-toxicity compound, climbazole has low skin and mucous membrane irritation and high safety. When used at the prescribed dosage, it will not burden the scalp and hair. It also possesses broad-spectrum antibacterial properties, effectively inhibiting various harmful bacteria such as Candida albicans and Trichophyton mentagrophytes, providing more options for personal care products.
Application Areas
1. Personal Care
Climbazole is most commonly used in various personal care products. In shampoos and conditioners, the commonly recommended addition level is 0.4% - 1.0% (maximum allowable concentration is 2%), effectively addressing dandruff. It is also widely added to shower gels and antibacterial soaps to help cleanse the skin and inhibit bacterial growth.
2. Oral Care
Climbazole is also used in products such as toothpaste and mouthwash, effectively preventing and improving oral problems such as gingivitis and periodontitis, maintaining the balance of the oral microecology.
3. Others
In the pharmaceutical field, climbazole can be used as an active ingredient in antifungal drugs to treat fungal skin infections such as tinea pedis, tinea corporis, and tinea cruris. It is also used as an adjunct in the formulation of eczema medications to help relieve skin discomfort.
Choose YTBIO Climbazole (99% purity), which gives your products excellent dandruff-reducing and anti-itch effects, making it a core ingredient for creating high-quality daily chemical products. If you are interested in YTBIO's Climbazole or other functional ingredients, please feel free to contact us via online consultation or by email.
Email：sales@sxytbio.com
WhatsApp/phone：+86 17782577059
